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Dr. Chan, headshot

Dr. Edward Chan, MD

Dermatologist & Dermatopathologist

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Clinical Specialty



Board Certification



Clinical Expertise

Clinical Dermatology


Education & Training

Massachusetts Institute of Technology – 1989, BS, biology

Harvard Medical School – 1994, MD with Honors, Cum de Laude

University of Pennsylvania – 1998, Residency in Dermatology, Chief Resident

University of Pennsylvania – 2000, Fellowship in Dermatopathology

Professional Membership

American Society of Dermatopathology

American Academy of Dermatology

Pennsylvania Academy of Dermatology and Dermatologic Surgery

Managing editor, Dermatology Online Textbook, Emedicine

Faculty Appointments

Present | Clinical Associate Professor of Dermatology, Department of Dermatology, Hospital of the University of Pennsylvania

Academic & Teaching Responsibilities

Volunteer Attending, Department of Dermatology Resident Clinic, Hospital of the University of Pennsylvania

Annual Presenter, Penn Dermatopathology Lecture Series

Awards & Honors

1988 Sigma Xi Research Society

1988 Burchard Scholar for excellence in humanities

1992 Howard Hughes Medical Institute - NIH Research Scholarship for Medical Students

1998 Philippine Chinese-American Physician’s Association Outstanding Young Physician Award

1998 Howard Hughes Medical Institute Postdoctoral Research Fellowship for Physicians

1999 American Society of Dermatopathology Award for Residents and Fellows, “Best Oral Abstract”

2000 American Academy of Dermatology Young Investigator Award

2016 ​Duhring Clinic Attending of the Year for excellence in teaching

Research / Publications

  1.  Hengge UR, Chan EF, Foster RA, Walker PS, and Vogel JC.  Cytokine gene expression in epidermis with biological effects following       injection of naked DNA.  Nature Genetics 10: 161-166, 1995.
  2.  Hengge UR, Chan EF, Hamshire V, Foster RA, and Vogel JC.  The derivation and characterization of pig keratinocyte cell lines that       retain the ability to differentiate.  J Invest Dermatol 106: 287-93, 1996.
  3.  Chan EF and Mowad C.  Contact dermatitis to foods and spices.  American Journal of Contact Dermatitis 9: 71-79, 1998.
  4.  Chan E, Thakur A, Farid L, Lessin SL, Uberti-Benz M, James W.  Pemphigus vulgaris of the cervix and upper vaginal vault: a cause of atypical Papanicolau smears.  Archives of Dermatology 134: 1485-1486, 1998.
  5.  Chan EF, Dowdy YG, Lee B, McKenna WG, Levy RJ, Wasik MA, Rook AH. A novel chemotherapeutic regimen (interferon-alfa, zidovudine, and etretinate) for adult T-cell lymphoma resulting in rapid tumor destruction.  Journal of the American Academy of Dermatology 40: 116-21, 1999.
  6.  Chan EF, Gat U, McNiff J, Fuchs E.  A common human skin tumor is caused by activating mutations in beta-catenin.  Nature Genetics 21:410-413, 1999.
  7.  Hsuing SH, Chan EF, Elenitsas RE, Kolasinski S, Schumacher HR, Werth VP.  Multicentric reticulohistiocytosis presenting with clinical features of dermatomyositis.  Journal of the American Academy of Dermatology, 48:S11-14, 2003.
  8.  Chan EF. Alopecia and its medical management.  Facial Plastic Surgery Clinics of North America, 11:267-276, 2003.
  9. Vincent A, Farley M, Chan E, James WD.  Birt-Hogg-Dube syndrome: A review of the literature and the differential diagnosis of firm facial papules. Journal of the American Academy of Dermatology 49: 698-705, 2003.
  10.  Vincent A, Farley M, Chan E, James WD.  Birt-Hogg-Dube syndrome: Two patients with neural tissue tumors.  Journal of the American Academy of Dermatology 49: 717-719, 2003.
  11.  Walther BS, Gibbons G, Chan EF, Ziselman E, Rothfleisch JE, Willard RJ, Baldassano MF. Leukemia cutis (involving chronic lymphocytic leukemia) within excisional specimens: a series of 6 cases. Am J Dermatopathol 31(2):162-5, 2009.
  12.  Morrissey K, Bennett D, Burkert K, Chan E, Elenitsas R.  Pleomorphic hyalinizing angiectatic tumor of soft parts:  a case report. American Society of Dermatopathology Meeting, Seattle, WA.  October 20-23, 2011.
  13.  Imadojemu S, Elenitsas R, Chan E, Wanat K, Rosenbach M. Multiple granulomatous dermatitides in a patient with rheumatoid arthritis. JAAD Case Reports 2(1):67-9, 2016.
  14.  Dai J, Kunder CA, Chu EY, Chan EF, Egan CE, Novoa RA. Development of RET mutant cutaneous angiosarcoma during BRAF inhibitor therapy. Journal of Cutaneous Pathology 44 (12):1053-56, 2017.
  15.  Tan J, Loh K, Thakur K, Chan EF, Ghaneie A. A Sweet diagnosis for a non-resolving rash. Cureus 10(4): e2516, 2018.
  16.  Xiang Y, Moshiri AS, Chan EF, Dasgupta TS, Kozic H, Elenitsas R, Nguyen CV. There is fat in this sclerosis: A case report of sclerotic lipoma and review of the literature. Journal of Cutaneous Pathology 47:286-90, 2020.